MiNa Faculty Member

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Dr. Karen Cheung

2332 Main Mall, Vancouver, BC Canada V6T 1Z4 Tel: +1 604.827.4114 Fax: +1 604.822.5949 http://www.ece.ubc.ca/~kcheung/ Email: Education B.S. 1998, University of California Berkeley Ph.D. 2002, University of California Berkeley Research Interests bioMEMS, implantable microelectrodes, lab-on-a-chip devices, microfluidics Courses See ECE web page for course list.

Group Members: Ali Ahmadi, Visiting / Post-Doc student Nina Buffi, Visiting / Post-Doc student Kevin Han, Visiting / Post-Doc student Yu Linfen, Visiting / Post-Doc student Samantha Grist, Ph.D. student Eric Ouellet, Ph.D. student Michael C Chen, M.A.Sc. student Christopher Flory, M.A.Sc. student Dhruti Trivedi, M.A.Sc. student Mona Nematifar, B.A.Sc. student Shabnam Parsa, B.A.Sc. student Ryan Schilling, B.A.Sc. student Philip Tsao, B.A.Sc. student Michael Vass, B.A.Sc. student Jonas Flueckiger, student Madhuja Gupta, student Alumni: Frederic Loizeau, Visiting / Post-Doc Arash Zargaran Yazd, M.A.Sc.

Research Projects

Reversible cell trapping in microfluidic channels using hydrogels	Reversible cell trapping in microfluidic channels using hydrogels
Biocompatible coatings for implantable polymer-based multielectrode arrays	Biocompatible coatings for implantable polymer-based multielectrode arrays

Journal Publications

(Table View)

In Press

Michael C.W. Chen, Karen C. Cheung, "Hydrogel-based microfluidic cell culture", Biomaterials for MEMS: Pan Stanford Publishing, In Press  . Tagged XML BibTex

2013

Xu Wang, Jonas Flueckiger, Shon Schmidt, Samantha Grist, Sahba T. Fard, James Kirk, Matt Doerfler, Karen C. Cheung, Daniel M. Ratner, and Lukas Chrostowski, "A silicon photonic biosensor using phase-shifted Bragg gratings in slot waveguide", J. Biophotonics, 04/2013. Abstract Tagged XML BibTex

Samantha M. Grist, Shon A. Schmidt, Jonas Flueckiger, Valentina Donzella, Wei Shi, Sahba Talebi Fard, James T. Kirk, Daniel M. Ratner, Karen C. Cheung, Lukas Chrostowski, "Silicon photonic micro-disk resonators for label-free biosensing", Optics Express, vol. 21, issue 7: The Optical Society, pp. 7994–8006, 03/2013. Abstract Tagged XML BibTex

Talebi Fard, Sahba, Grist, Samantha M., Donzella, Valentina, Schmidt, Shon A., Flueckiger, Jonas, Wang, Xu, Shi, Wei, Millspaugh, Andrew, Webb, Mitchell, Ratner, Daniel M., Cheung, Karen C., Chrostowski, Lukas, "Label-free silicon photonic biosensors for use in clinical diagnostics", Proc. SPIE, Silicon Photonics VIII, vol. 8629, issue 862909, pp. 862909--14, 02/2013. Abstract Tagged XML BibTex

2012

S. M. Grist, L. Chrostowski, K. C. Cheung, "Thin Film Patterning using a Water-Soluble Etch Mask", 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Okinawa, Japan, 28/10/2012. Tagged XML BibTex

Daljeet Chahal, Ali Ahmadi, Karen C. Cheung, "Improving piezoelectric cell printing accuracy and reliability through neutral buoyancy of suspensions", Biotechnology and Bioengineering: Wiley Periodicals, Inc., 06/2012. Abstract Tagged XML BibTex

Lukas Chrostowski, Samantha Grist, Jonas Flueckiger, Wei Shi, Xu Wang, Eric Ouellet, Han Yun, Mitch Webb, Ben Nie, Zhen Liang, Karen C. Cheung, Shon A. Schmidt, Daniel M. Ratner, Nicolas A. F. Jaeger, "Silicon photonic resonator sensors and devices", Proceedings of SPIE Volume 8236; Laser Resonators, Microresonators, and Beam Control XIV, 01/2012. Abstract Tagged XML BibTex

2011

Jonas Flueckiger, Vahid Bazargan, Boris Stoeber, Karen Cheung, "Characterization of postfabricated parylene C coatings inside PDMS microdevices", Sensors and Actuators B: Chemical , vol. 160, issue 1: Elsevier, pp. 864-874, 12/2011. Tagged XML BibTex

Jonas Flueckiger, Samantha M. Grist, Eric Ouellet, Lukas Chrostowski, Karen C. Cheung, "Label-Free Biosensing Using Cascaded Silicon-on-Insulator Micro-Racetrack Resonators Integrated With PDMS Microfluidic Channels", The 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Seattle, Washington, USA, 10/2011. Abstract Tagged XML BibTex

Jonas Flueckiger, Samantha M. Grist, Gurpal Bisra, Lukas Chrostowski, Karen C. Cheung, "Cascaded silicon-on-insulator microring resonators for the detection of biomolecules in PDMS microfluidic channels", Proc. SPIE, Vol 7929; SPIE Microfluidics, BioMEMS, and Medical Microsystems IX, 01/2011. Tagged XML BibTex

2010

Samantha M. Grist, Lukas Chrostowski, Karen C. Cheung, "Optical Oxygen Sensors for Applications in Microfluidic Cell Culture", Sensors, vol. 10, issue 10: MDPI Publishing, Basel, Switzerland , pp. 9286-9316, 10/2010. Abstract Tagged XML BibTex

MCW Chen, M Gupta, KC Cheung, "Alginate-based microfluidic system for tumor spheroid formation and anticancer agent screening", Biomedical Microdevices, 03/2010. Tagged XML BibTex

Samantha M. Grist, Jonas Flueckiger, Jiali Yu, Wei Shi, Karen C. Cheung, Lukas Chrostowski, "Silicon-on-insulator resonators integrated with PDMS microfluidic channels for applications in biosensing", Pacific Center for Advanced Materials and Microstructures (PCAMM) 15th Annual Meeting, 2010  . Tagged XML BibTex

2009

J Flueckiger, FK Ko, KC Cheung, "Microfabricated Formaldehyde Gas Sensors", Sensors, vol. 9, issue 11, pp. 9196-9215, 11/2009. Tagged XML BibTex

J Flueckiger, KC Cheung, "Microfluidic System for Controlled Gelation of a Thermally Reversible Hydrogel", IEEE Transactions on Biomedical Circuits and Systems, vol. 3, issue 4, pp. 195-201, 08/2009. Tagged XML BibTex

MCW Chen, M Gupta, KC Cheung, "Hydrogel-Based Microfluidic System for Cell-Based Anticancer Agent Screening", 13th International Conference on Miniaturized Systrems for Chemistry and Life Sciences. Micro Total Analysis Systems (MicroTAS 2009), Jeju, South Korea, 01/11/2009. Tagged XML BibTex

Karen C. Cheung, "Thin-film microelectrode arrays for biomedical applications", Implantable Neural Prostheses: Techniques and Applications: Springer, pp. 157-190, 2009  . Tagged XML BibTex

2008

Jonas Flueckiger, Karen C. Cheung, "Locally Defined Thermally Reversible Hydrogel Formation in Microchannels", 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Micro Total Analysis Systems (MicroTAS 2008), 10/2008. Tagged XML BibTex

Michael C.W. Chen, Madhuja Gupta, Karen C. Cheung, "Hydrogel-based microfluidic systems for co-culture of cells", 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 08/2008. Tagged XML BibTex

Jonas Flueckiger, Karen C. Cheung, "Integrated microfluidic systems for cell culture and characterization", 14th IEEE International Mixed-Signals, Sensors, and Systems Test Workshop, 06/2008. Tagged XML BibTex

Mercanzini, André, Cheung, Karen, Buhl, Derek L., Boers, Marc, Maillard, Anne, Colin, Philippe, Bensadoun, Jean-Charles, Bertsch, Arnaud, Renaud, Philippe, "Demonstration of cortical recording using novel flexible polymer neural probes", Sensors and Actuators A: Physical, vol. 143, issue 1, 05/2008. Tagged XML BibTex

2007

Mercanzini, Andre, Karen C Cheung, Derek Buhl, Marc Boers, Anne Maillard, Philippe Colin, Jean-Charles Bensadoun, Arnaud Bertsch, Alan Carleton, Philippe Renaud, "Demonstration of Cortical Recording and Reduced Inflammatory Response Using Flexible Polymer Neural Probes", 20th IEEE International Conference on MEMS, Kobe, Japan, pp. 573-576, 2007  . Tagged XML BibTex

Karen C Cheung, Philippe Renaud, Heikki Tanila, Kaj Djupsund, "Flexible polyimide microelectrode array for in vivo recordings and current source density analysis", Biosensors and Bioelectronics, vol. 22, no. 8, pp. 1783-1790, 2007  . Tagged XML BibTex

Karen C Cheung, "Implantable Microscale Neural Interfaces", Biomedical Microdevices, 2007  . Tagged XML BibTex

2006

Karen C Cheung, Philippe Renaud, Heikki Tanila, Kaj Djupsund, "Flexible Microelectry Array: in vivo Recording and Tissue Reaction", 29th Canadian Medical and Biological Engineering Conference, Vancouver, Canada, 2006  . Tagged XML BibTex

Andre Mercanzini, Karen C Cheung, Arnaud Bertsch, Philippe Renaud, "The Lausanne Neuroprosthesis: A Flexible Polyimide Microelectrode for Acute and Chronic Cortical Recordings", The EPFL LATSIS Symposium 2006, Lausanne, Switzerland, pp. 109-110, 2006  . Tagged XML BibTex

Cheung, Karen C., Renaud, Philippe, "BioMEMS for medicine: On-chip cell characterization and implantable microelectrodes", Solid-State Electronics, vol. 50, no. 4, pp. 551-557, 2006  . Tagged XML BibTex

2005

Karen C Cheung, Philippe Renaud, "BioMEMS in Medicine: Diagnostic and Therapeutic Systems", 35th European Solid-State Device Research Conference, Grenoble, France, pp. 345-350, 2005  . Tagged XML BibTex

Karen C Cheung, Yinghui Zhong, Philippe Renaud, Ravi Bellamkonda, "Comparison of Tissue Reaction to Implanted Polyimide and Silicon Microelectrode Arrays", Biosurf VI - Tissue-Surface Interaction, Lausanne, Switzerland, 2005  . Tagged XML BibTex

Karen C. Cheung, Shady Gawad, Philippe Renaud, "Impedance spectroscopy flow cytometry: On-chip label-free cell differentiation", Cytometry Part A, vol. 65A, no. 2, pp. 124-132, 2005  . Tagged XML BibTex

2004

Shady Gawad, Karen C. Cheung, Urban Seger, Arnaud Bertsch, Philippe Renaud, "Dielectric spectroscopy in a micromachined flow cytometer: theoretical and practical considerations", Lab on a Chip, vol. 4, pp. 241-251, 2004  . Tagged XML BibTex

Karen C. Cheung, Shady Gawad, Philippe Renaud, "Impedance Spectroscopy Flow Cytometry: Parameters for Label-Free Cell Differentiation", 8th International Conference on Micro Total Analysis Systems, Malmö, Sweden, pp. 55-57, 2004  . Tagged XML BibTex

Shady Gawad, Karen C. Cheung, Philippe Renaud, "Impedance Spectroscopy Flow Cytometry: Model Validation", 8th International Conference on Micro Total Analysis Systems, Malmö, Sweden, pp. 58-60, 2004  . Tagged XML BibTex

Karen C. Cheung, Shady Gawad, Philippe Renaud, "Microfluidic Impedance Spectroscopy Flow Cytometer: Particle Size Calibration", 17th IEEE International Conference on MEMS, Maastricht, The Netherlands, pp. 343-346, 2004  . Tagged XML BibTex

2003

Cheung, Karen C., Djupsund, Kaj, Dan, Yang, Lee, Luke P, "Implantable multichannel electrode array based on SOI technology", Microelectromechanical Systems, Journal of, vol. 12, no. 2, pp. 179-184, 2003  . Tagged XML BibTex

Ionescu-Zanetti, Cristian, Cheung, Karen C., Lal, Ratneshwar, Lee, Luke P., "Simultaneous imaging of ionic conductivity and morphology of a microfluidic system", Journal of Applied Physics, vol. 93, no. 12: AIP, pp. 10134-10136, 2003  . Tagged XML BibTex

2002

Karen C. Cheung, Tim Kubow, Luke P Lee, "Individually Addressable Planar Patch Clamp Array", 2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology, Madison, USA, pp. 72-76, 2002  . Tagged XML BibTex

Tim Kubow, Karen C. Cheung, Loren F Bentley, Luke P Lee, "Microfabricated Patch Clamp Array for Neural MEMS Applications", Materials Research Society Spring 2002 Meeting, San Francisco, USA, 2002  . Tagged XML BibTex

Karen C. Cheung, Yang-Kyu Choi, Tim Kubow, Luke P Lee, "Nanostructured Electrodes for Neural Chip Applications", 6th International Conference on Micro Total Analysis Systems, Nara, Japan, pp. 778-780, 2002  . Tagged XML BibTex

Karen C. Cheung, Yang-Kyu Choi, Tim Kubow, Luke P Lee, "Nanostructured Electrodes for Improved Neural Recording", Materials Research Society Spring 2002 Meeting, San Francisco, USA, 2002  . Tagged XML BibTex

2000

Karen C. Cheung, Gun Lee, Kaj Djupsund, Yang Dan, Luke P Lee, "A new neural probe using SOI wafers with topological interlocking mechanisms", 1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology, Lyon, France, pp. 507-511, 2000  . Tagged XML BibTex

1999

Barth, Phillip W., McAllister, William H., Hoen, Storrs, Cheung, Karen C., Gas-flow management using capillary capture and thermal release, , no. 440834, USA, Agilent Technologies Inc., 1999  . Tagged XML BibTex

1997

Tejal A Desai, Karen C. Cheung, WH Chu, Mauro Ferrari, "In vitro immunoisolative properties of microfabricated biocapsules", 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Chicago, USA, pp. 2578-2581, 1997  . Tagged XML BibTex

History

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Member for

6 years 7 weeks