Photoacoustic Tissue Imaging
This project aims to design a photoacoustic imaging system for prostate cancer study. Images will be acquired by using a laser to excite acoustic waves from tissues and an ultrasound transducer array to detect the acoustic waves. The photoacoustic imaging will be combined with ultrasound imaging to study prostate cancer.
Photoacoustic imaging is an emerging field which can perform non-invasive, functional imaging for up to several centimeters in live tissues. In photoacoustic imaging, high energy laser pulses are delivered to tissues. Upon absorbing the laser pulses, ultrasound waves are generated due to localized heating and thermal expansion. An ultrasound detector array collects the ultrasound waves. 2D or 3D images can be reconstructed based on beam scanning and detection of the time-of-flight of the ultrasound waves. Photoacoustic imaging can be used in combination with ultrasound imaging, where ultrasound will provide structural imaging and photoacoustic will provide functional imaging of the distribution of total hemoglobin and blood oxygenation. The photoacoustic imaging will be combined with ultrasound imaging to study prostate cancer.